Consortin

Protein found in humans
CNST
Identifiers
AliasesCNST, C1orf71, PPP1R64, consortin, connexin sorting protein
External IDsOMIM: 613439; MGI: 2445141; HomoloGene: 17139; GeneCards: CNST; OMA:CNST - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for CNST
Genomic location for CNST
Band1q44Start246,566,444 bp[1]
End246,668,595 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for CNST
Genomic location for CNST
Band1|1 H4Start179,373,935 bp[2]
End179,455,043 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • middle temporal gyrus

  • spinal ganglia

  • secondary oocyte

  • vastus lateralis muscle

  • deltoid muscle

  • Skeletal muscle tissue of rectus abdominis

  • trigeminal ganglion

  • visceral pleura

  • gastrocnemius muscle

  • lateral nuclear group of thalamus
Top expressed in
  • vestibular membrane of cochlear duct

  • primary oocyte

  • zygote

  • blood

  • habenula

  • Epithelium of choroid plexus

  • extraocular muscle

  • retinal pigment epithelium

  • secondary oocyte

  • knee joint
More reference expression data
BioGPS




More reference expression data
Gene ontology
Molecular function
  • phosphatase binding
  • protein binding
  • connexin binding
Cellular component
  • integral component of membrane
  • trans-Golgi network
  • plasma membrane
  • Golgi apparatus
  • transport vesicle
  • membrane
  • cytoplasmic vesicle
  • intracellular membrane-bounded organelle
  • protein-containing complex
Biological process
  • negative regulation of phosphatase activity
  • positive regulation of Golgi to plasma membrane protein transport
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

163882

226744

Ensembl

ENSG00000162852

ENSMUSG00000038949

UniProt

Q6PJW8

Q8CBC4

RefSeq (mRNA)

NM_001139459
NM_152609

NM_146105

RefSeq (protein)

NP_001132931
NP_689822

NP_666217

Location (UCSC)Chr 1: 246.57 – 246.67 MbChr 1: 179.37 – 179.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Consortin (CNST) is a protein that in humans is encoded by the CNST gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162852 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038949 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: C1orf71 chromosome 1 open reading frame 71".

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.


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