DIS3L2 |
---|
|
Identifiers |
---|
Aliases | DIS3L2, FAM6A, PRLMNS, hDIS3 like 3'-5' exoribonuclease 2 |
---|
External IDs | OMIM: 614184; MGI: 2442555; HomoloGene: 62417; GeneCards: DIS3L2; OMA:DIS3L2 - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
---|
| Band | 2q37.1 | Start | 231,961,245 bp[1] |
---|
End | 232,344,350 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
---|
| Band | 1|1 C5 | Start | 86,631,530 bp[2] |
---|
End | 86,977,817 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - sural nerve
- sperm
- buccal mucosa cell
- right uterine tube
- right lobe of thyroid gland
- right testis
- left testis
- Achilles tendon
- left lobe of thyroid gland
- left ovary
|
| Top expressed in | - spermatid
- Rostral migratory stream
- hand
- spermatocyte
- lumbar spinal ganglion
- lens
- muscle of thigh
- genital tubercle
- lumbar subsegment of spinal cord
- neural tube
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Gene ontology |
---|
Molecular function | - 3'-5'-exoribonuclease activity
- poly(U) RNA binding
- metal ion binding
- ribonuclease activity
- protein binding
- RNA binding
- nuclease activity
- exonuclease activity
- hydrolase activity
- magnesium ion binding
| Cellular component | - cytoplasm
- polysome
- P-body
- exosome (RNase complex)
| Biological process | - miRNA catabolic process
- nucleic acid phosphodiester bond hydrolysis
- nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
- cell division
- stem cell population maintenance
- rRNA processing
- cell cycle
- mitotic sister chromatid separation
- negative regulation of cell population proliferation
- RNA phosphodiester bond hydrolysis, exonucleolytic
- RNA phosphodiester bond hydrolysis
- nuclear-transcribed mRNA catabolic process, exonucleolytic
- polyuridylation-dependent mRNA catabolic process
- mitotic cell cycle
- RNA catabolic process
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_001257281 NM_001257282 NM_152383 |
| |
---|
RefSeq (protein) | |
---|
NP_001244210 NP_001244211 NP_689596 |
| |
---|
Location (UCSC) | Chr 2: 231.96 – 232.34 Mb | Chr 1: 86.63 – 86.98 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|