HES2 |
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Identifiers |
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Aliases | HES2, bHLHb40, hes family bHLH transcription factor 2 |
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External IDs | OMIM: 609970; MGI: 1098624; HomoloGene: 22455; GeneCards: HES2; OMA:HES2 - orthologs |
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Gene location (Human) |
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![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
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| Band | 1p36.31 | Start | 6,412,418 bp[1] |
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End | 6,424,670 bp[1] |
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Gene location (Mouse) |
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![Chromosome 4 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/9/9c/Ideogram_house_mouse_chromosome_4.svg/260px-Ideogram_house_mouse_chromosome_4.svg.png) | Chr. | Chromosome 4 (mouse)[2] |
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| Band | 4 E2|4 82.92 cM | Start | 152,243,324 bp[2] |
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End | 152,246,926 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - mucosa of esophagus
- mucosa of transverse colon
- buccal mucosa cell
- placenta
- skin of abdomen
- gingival epithelium
- skin of leg
- vagina
- right uterine tube
- olfactory zone of nasal mucosa
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| Top expressed in | - embryo
- lip
- jejunum
- right kidney
- proximal tubule
- duodenum
- yolk sac
- Ileal epithelium
- esophagus
- lens
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - DNA binding
- double-stranded DNA binding
- transcription factor binding
- protein dimerization activity
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- DNA-binding transcription factor activity, RNA polymerase II-specific
- RNA polymerase II transcription regulatory region sequence-specific DNA binding
- transcription corepressor activity
- sequence-specific DNA binding
- sequence-specific double-stranded DNA binding
| Cellular component | | Biological process | - negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- somitogenesis
- Notch signaling pathway
- cell differentiation
- regulation of neurogenesis
- anterior/posterior pattern specification
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 6.41 – 6.42 Mb | Chr 4: 152.24 – 152.25 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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